There are two main approaches to how statistical patterns are extracted from sequences: The transitional probability approach proposes that statistical learning occurs through the computation of probabilities between items in a sequence. The chunking approach, including models such as PARSER and TRACX, proposes that units are extracted as chunks. Importantly, the chunking approach suggests that the extraction of full units weakens the processing of subunits while the transitional probability approach suggests that both units and subunits should strengthen. Previous findings using (...) sequentially organized, auditory stimuli or spatially organized, visual stimuli support the chunking approach. However, one limitation of prior studies is that most assessed learning with the two-alternative forced-choice task. In contrast, this pre-registered experiment examined the two theoretical approaches in sequentially organized, visual stimuli using an online self-paced task—arguably providing a more sensitive index of learning as it occurs—and a secondary offline familiarity judgment task. During the self-paced task, abstract shapes were covertly organized into eight triplets (ABC) where one in every eight was altered (BCA) from the canonical structure in a way that disrupted the full unit while preserving a subunit (BC). Results from the offline familiarity judgment task revealed that the altered triplets were perceived as highly familiar, suggesting the learned representations were relatively flexible. More importantly, results from the online self-paced task demonstrated that processing for subunits, but not unit-initial stimuli, was impeded in the altered triplet. The pattern of results is in line with the chunking approach to statistical learning and, more specifically, the TRACX model. (shrink)

Speakers of different languages (e.g., English vs. Turkish) show a binary split in how they package and order components of a motion event in speech and co‐speech gesture but not in silent gesture. In this study, we focused on Mandarin Chinese, a language that does not follow the binary split in its expression of motion in speech, and asked whether adult Chinese speakers would follow the language‐specific speech patterns in co‐speech but not silent gesture, thus showing a pattern akin to (...) Turkish and English adult speakers in their description of animated motion events. Our results provided evidence for this pattern, with Chinese—as well as English and Turkish—speakers following language‐specific patterns in speech and co‐speech gesture but not in silent gesture. Our results provide support for the “thinking‐for‐speaking” account, namely that language influences thought only during online, but not offline, production of speech. (shrink)

Socioeconomic status -related health disparities persist for numerous chronic diseases, with lower-SES individuals exhibiting greater risk of morbidity and mortality compared to their higher-SES counterparts. One likely contributor is disparities in health messaging efforts, which are currently less effective for motivating health behavior change among those lower in SES. Drawing on communication neuroscience and social neuroscience research, we describe a conceptual framework to improve health messaging effectiveness in lower SES communities. The framework is based on evidence that health-message-induced activity in (...) the ventral striatum and subdivisions of the medial pre-frontal cortex predicts behavior change. Additionally, we draw from social neuroscience work showing that activity in these regions during valuation and the processing of self-related vs. social information, differs as a function of SES. Bringing together these previously disparate lines of work, we argue that health messages emphasizing the benefits to close others of engaging in behavior change will be more effective among lower SES individuals. We also outline a research agenda based on our framework. Ultimately, we hope that this framework utilizing a “brain-as-predictor” approach generates novel insights about the neural underpinnings of message-induced behavior change among lower SES individuals, and helps to close the gap in SES-based health disparities by harnessing the power of neuroimaging. (shrink)

This paper examines ways in which Nazism has been sexualized in contemporary Western media, drawing on Foucault’s theory of biopower to explain this bizarre phenomena. I argue Nazism has been eroticized through its use as a floating signifier for “evil” or “abnormal,” the oppositional half of the hegemonic binary narrative. Looking to Foucault’s later work on resistance and perfectionist ethics, I ultimately argue these representations negatively detract from and silence survivor and witness testimony, problematically distorting popular knowledge and understanding of (...) the Shoah to fit hegemonic binary narratives, rather than to pay respect to or preserve the stories and suffering of the victims. (shrink)

Recent ethical breeches by corporate governorsat the highest levels have called into questionwhether ethical attitudes have changed sincethe Corporate Raider scandals of the mid-1980s. We exploit a unique opportunity to follow-up ona previous investigation of college students inthe mid-1980s to analyze this question. Usinga similar survey instrument, we find thatstudents surveyed in 2001 are significantlyless accepting of the ethically questionablesituations in seven of 15 scenarios and moreaccepting in only one. Seven scenarios showedno significant change. We conclude that,overall, ethical attitudes of (...) students in 2001appear to have become higher over time. To theextent that current students are futurebusiness leaders, we find these results to beencouraging for the long term. (shrink)

Recent highly publicized ethical breaches including those at Enron and WorldCom have focused attention on ethical behavior within the accounting profession. At the heart of the debate is whether ethical attitudes of accountants are to blame. Using a nationally representative sample of accounting practitioners and a multidisciplinary student sample at two Southern United States universities, we compare sample responses to 25 ethically charged vignettes to test whether they differ. Overall, we find no significant difference - even for a specific "accounting (...) tricks" vignette, which resembles the Enron and WorldCom situations. We do find, however, that the practitioners were more accepting of vignettes that involved physical harm to individuals and those that were legal. We postulate that accounting practitioners may apply a legalistic framework to their assessment of the acceptability of each vignette. Focusing on an "accounting tricks" vignette, we also find no significant difference between auditors and institutional practitioners compared to all other types of accountants in the sample. We conclude that ethical attitudes of accounting practitioners do not differ significantly by specialty area. (shrink)

Trust has been identified as an indicator within Social Quality theory. As an important component of social quality, trust has become increasingly important in modern society because literature suggests that trust in a number of democratic countries is declining. Modern technologies and specialties are often beyond the understanding of lay individuals and thus, the need for trusting relations between lay individuals and organizations/individuals has grown. The purpose of the study was to examine the extent to which Australians (dis)trust individuals and (...) organizations/institutions. A national postal survey was conducted with 1,044 respondents recruited using the electronic white pages directory. Findings from multivariate analyses suggest that income, age, sex, and health status are associated with trust in groups of individuals and trust in organizations/institutions. The findings highlight populations where trust needs to be (re)built. Future government policy and practice should utilize these findings as a means of facilitating social quality. (shrink)

Perhaps the central focus of American bioethics has been to push against medical paternalism on the grounds that it impedes the autonomy of patients—that is, their ability to make choices of their...

What role does experience play in the development of face recognition? A growing body of evidence indicates that newborn brains need slowly changing visual experiences to develop accurate visual recognition abilities. All of the work supporting this “slowness constraint” on visual development comes from studies testing basic‐level object recognition. Here, we present the results of controlled‐rearing experiments that provide evidence for a slowness constraint on the development of face recognition, a prototypical subordinate‐level object recognition task. We found that (1) newborn (...) chicks can rapidly develop view‐invariant face recognition and (2) the development of this ability relies on experience with slowly moving faces. When chicks were reared with quickly moving faces, they built distorted face representations that largely lacked invariance to viewpoint changes, effectively “breaking” their face recognition abilities. These results provide causal evidence that slowly changing visual experiences play a critical role in the development of face recognition, akin to basic‐level object recognition. Thus, face recognition is not a hardwired property of vision but is learned rapidly as the visual system adapts to the temporal structure of the animal's visual environment. (shrink)

How do newborns learn to recognize objects? According to temporal learning models in computational neuroscience, the brain constructs object representations by extracting smoothly changing features from the environment. To date, however, it is unknown whether newborns depend on smoothly changing features to build invariant object representations. Here, we used an automated controlled-rearing method to examine whether visual experience with smoothly changing features facilitates the development of view-invariant object recognition in a newborn animal model—the domestic chick. When newborn chicks were reared (...) with a virtual object that moved smoothly over time, the chicks created view-invariant representations that were selective for object identity and tolerant to viewpoint changes. Conversely, when newborn chicks were reared with a temporally non-smooth object, the chicks developed less selectivity for identity features and less tolerance to viewpoint changes. These results provide evidence for a “smoothness constraint” on the development of invariant object recognition and indicate that newborns leverage the temporal smoothness of natural visual environments to build abstract mental models of objects. (shrink)

We address a previous finding in the business ethics literature in which accounting professionals in higher rank levels, i.e., “manager” or “partner” of auditing firms, appear to have lower moral reasoning ability than their junior counterparts. Prior investigations have relied upon a similar methodology for estimating ethical beliefs, namely testing “moral reasoning ability” using either the Moral Judgment Interview or Defining Issues Test. In the present study, we use a multiple vignettes approach to test for the existence of the inverse (...) rank-ethical beliefs effect. With only 2 of the 30 vignettes resulting in both managers and partners being more accepting of the ethically charged behaviors, the results presented here using this alternative methodology are generally not supportive of the inverse rank-ethical beliefs phenomenon. We also use a multivariate analysis in order to control for demographic characteristics. Our results suggest that the most robust predictor of ethical attitudes among accounting practitioners is age, not rank within a firm. (shrink)

Cannabis sativa L. is grown and marketed under a large number of named strains. Strains are often associated with phenotypic traits of interest to consumers, such as aroma and cannabinoid content. Yet genetic inconsistencies have been noted within named strains. We asked whether genetically inconsistent samples of a commercial strain also display inconsistent aroma profiles. We genotyped 32 samples using variable microsatellite regions to determine a consensus strain genotype and identify genetic outliers for four strains. Results were used to select (...) 15 samples for olfactory testing. A genetic outlier sample was available for all but one strain. Aroma profiles were obtained by 55 sniff panelists using quantitative sensory evaluation of 40 odor descriptors. Within a strain, aroma descriptor frequencies for the genetic outlier were frequently at odds with those of the consensus samples. It appears that within-strain genetic differences are associated with differences in aroma profile. Because these differences were perceptible to untrained panelists, they may also be noticed by retail consumers. Our results could help the cannabis industry achieve better control of product consistency. (shrink)

We survey students at two Southern United States universities (one public and one private, religiously affiliated). Using a survey instrument that includes 25 vignettes, we test two important hypotheses: whether ethical attitudes are affected by religiosity (H1) and whether ethical attitudes are affected by courses in ethics, religion or theology (H2). Using a definition of religiosity based on behavior (church attendance), our results indicate that religiosity is a statistically significant predictor of responses in a number of ethical scenarios. In seven (...) of the eight vignettes for which religiosity is significant, the effect is negative, implying that it reduces the acceptability of ethically-charged scenarios. Completion of ethics or religion classes, however, was a significant predictor of ethical attitudes in only two of the 25 vignettes (and in the expected direction). We also find that males and younger respondents appear to be more accepting of the ethically-questionable vignettes. We conclude that factors outside of the educational system may be more influential in shaping responses to ethical vignettes than are ethics and religion courses. (shrink)

We take up the challenge of developing an international network with capacity to survey the world's scientists on an ongoing basis, providing rich datasets regarding the opinions of scientists and scientific sub-communities, both at a time and also over time. The novel methodology employed sees local coordinators, at each institution in the network, sending survey invitation emails internally to scientists at their home institution. The emails link to a ‘10 second survey’, where the participant is presented with a single statement (...) to consider, and a standard five point Likert scale. In June 2023, a group of 30 philosophers and social scientists invited 20,085 scientists across 30 institutions in 12 countries to participate, gathering 6,807 responses to the statement 'Science has put it beyond reasonable doubt that COVID-19 is caused by a virus'. The study demonstrates that it is possible to establish a global network to quickly ascertain scientific opinion on a large international scale, with high response rate, low opt-out rate, and in a way that allows for significant (perhaps indefinite) repeatability. Measuring scientific opinion in this new way would be a valuable complement to currently available approaches, potentially informing policy decisions and public understanding across diverse fields. (shrink)

The ontologies of Slavoj Žižek and Gilles Deleuze are incommensurable. Rather than appropriate one at the expense of the other, this essay uses Žižek’s notion of parallax to think the two philosophers together, without mediation. Both Deleuze and Žižek provide mirrored philosophical images, with the point of divergence being absolute lack. Deleuze argues that lack, or the being of negation, is an error of representational understanding, while Žižek conceives his philosophy as being driven by absolute lack. A stark opponent of (...) Žižek’s precursor, Hegel, Deleuze rejects opposition as a constitutive feature of reality. However, Žižek mirrors Deleuze’s very concepts in his Lacanian reading of Hegel, while said concepts retain identical terms. For instance, Žižek calls l’objet petit a “difference,” while his term for absolute negation is “repetition,” and finally, he refers to his philosophical system as the “non-All”. These singular concepts in Žižek’s thought share an identical language with that of Deleuze. Deleuze’s philosophy is one of “difference,” while its mode of proliferation is “repetition,” and finally, he often refers to his philosophy as the “One-All”. Mapping these common terms that do not denote a common language, but incommensurable, inverse logics, it becomes evident that Deleuze and Žižek are mirror images of one another, infinitely fragmenting across the expanse of their respective positions. Thus, by triangulating ontology from their unique perspectives, a new ontological shift emerges—one that resists mediation and admixture. (shrink)

Recent high-profile corporate scandals are reminiscent of the corporate raider scandals of the 1980s, suggesting that ethical scandals may occur in waves. This article provides a framework for analysis of this question by suggesting that ethical attitudes may be cyclical about long-term secular trends. We provide some empirical evidence from previously published work for the existence of cycles as well as a potential mechanism for their propagation, namely widespread publicity about a particularly salient event, e.g., Enron. Further, we posit that (...) long-run secular trends would be affected through more deliberate, cognitive means, e.g., instruction in business ethics. We also discuss an important research implication, namely that traditional cross-sectional “book-end” studies surveying ethical attitudes at two different points in time may be unable to disentangle short-run cyclical movements from long-term secular trends. (shrink)

Russian thought has long been a hybrid of native and imported forms—or more accurately, native values were first conceptualized and systematized according to Western European categories. This essay considers select entries in the Handbook (primarily those discussing Hegel, Solovyov, Tolstoy, and twentieth-century prose writers) not from the perspective of “pure” or abstract philosophy, arguably a Western achievement, but in the context of three traditional Russian virtues: tselostnost’ [wholeness], lichnost’ [personhood], and organichnost’ [organicity]. Each of these virtues, or values, is paradoxical, (...) easily misconstrued, and easily abused. The essay ends speculatively on two studies: the personalist implications of Paul Contino’s exploration of “incarnational realism” in Dostoevsky, and Iain McGilchrist’s work on left- and right-hemispheres of the brain as contexts for the place of Russian thought in the larger world. (shrink)

À la suite des récentes décisions légales reconnaissant plus de deux parents à certains enfants canadiens, nous nous demandons s’il existe des raisons morales pour limiter à deux le nombre de parents qu’un enfant peut avoir. Nous examinons quelques arguments traditionnels soutenant cette position et nous trouvons qu’ils ne suffisent pas pour la justifier. Nous présentons aussi un argument inspiré par le travail de Brighouse et Swift au sujet des bienfaits d’être parent, et nous montrons qu’il n’est pas assez fort (...) pour soutenir la nécessité de limiter à deux le nombre de parents. En terminant, nous suggérons quelques autres façons de séparer de façon positive l’idée de «parent» des notions traditionnelles. (shrink)

Psychopathy is a disorder characterized by severe and frequent moral violations in multiple domains of life. Numerous studies have shown psychopathy-related limbic brain abnormalities during moral processing; however, these studies only examined negatively valenced moral stimuli. Here, we aimed to replicate prior psychopathy research on negative moral judgments and to extend this work by examining psychopathy-related abnormalities in the processing of controversial moral stimuli and positive moral processing. Incarcerated adult males (N = 245) completed a functional magnetic resonance imaging protocol (...) on a mobile imaging system stationed at the prison. Psychopathy was assessed using the Hare Psychopathy Checklist–Revised (PCL-R). Participants were then shown words describing three types of moral stimuli: wrong (e.g., stealing), not wrong (e.g., charity), and controversial (e.g., euthanasia). Participants rated each stimulus as either wrong or not wrong. PCL-R total scores were correlated with not wrong behavioral responses to wrong moral stimuli, and were inversely related to hemodynamic activity in the anterior cingulate cortex in the contrast of wrong > not wrong. In the controversial > noncontroversial comparison, psychopathy was inversely associated with activity in the temporal parietal junction and dorsolateral prefrontal cortex. These results indicate that psychopathy-related abnormalities are observed during the processing of complex, negative, and positive moral stimuli. (shrink)

We speculate with Hegel about language, critiquing interpretations of Hegel’s views on language given by Jim Vernon, John McCumber, Stephen Houlgate, and Michael N. Forster, as well as defending Sophisticated Radical Whorfianism from the objections of Maria Francisca Reines and Jesse Prinz. Prior to discussing Forster, we explicate Hegel’s views on mechanical memory. We conclude by discussing why, although thought grows up, it does not move out.

Pericytes, like vascular smooth muscle cells, are perivascular cells closely associated with blood vessels throughout the body. Pericytes are necessary for vascular development and homeostasis, with particularly critical roles in the brain, where they are involved in regulating cerebral blood flow and establishing the blood-brain barrier. A role for pericytes during neurovascular disease pathogenesis is less clear—while some studies associate decreased pericyte coverage with select neurovascular diseases, others suggest increased pericyte infiltration in response to hypoxia or traumatic brain injury. Here, (...) we used an endothelial loss-of-function Recombination signal binding protein for immunoglobulin kappa J region (Rbpj)/Notch mediated mouse model of brain arteriovenous malformation (AVM) to investigate effects on pericytes during neurovascular disease pathogenesis. We tested the hypothesis that pericyte expansion, via morphological changes, and Platelet-derived growth factor B/Platelet-derived growth factor receptor β (Pdgf-B/Pdgfrβ)-dependent endothelial cell-pericyte communication are affected, during the pathogenesis of Rbpj mediated brain AVM in mice. Our data show that pericyte coverage of vascular endothelium expanded pathologically, to maintain coverage of vascular abnormalities in brain and retina, following endothelial deletion of Rbpj. In Rbpj-mutant brain, pericyte expansion was likely attributed to cytoplasmic process extension and not to increased pericyte proliferation. Despite expanding overall area of vessel coverage, pericytes from Rbpj-mutant brains showed decreased expression of Pdgfrβ, Neural (N)-cadherin, and cluster of differentiation (CD)146, as compared to controls, which likely affected Pdgf-B/Pdgfrβ-dependent communication and appositional associations between endothelial cells and pericytes in Rbpj-mutant brain microvessels. By contrast, and perhaps by compensatory mechanism, endothelial cells showed increased expression of N-cadherin. Our data identify cellular and molecular effects on brain pericytes, following endothelial deletion of Rbpj, and suggest pericytes as potential therapeutic targets for Rbpj/Notch related brain AVM. (shrink)

We take up the challenge of developing an international network with capacity to survey the world’s scientists on an ongoing basis, providing rich datasets regarding the opinions of scientists and scientific sub-communities, both at a time and also over time. The novel methodology employed sees local coordinators, at each institution in the network, sending survey invitation emails internally to scientists at their home institution. The emails link to a ‘10 second survey’, where the participant is presented with a single statement (...) to consider, and a standard five-point Likert scale. In June 2023, a group of 30 philosophers and social scientists invited 20,085 scientists across 30 institutions in 12 countries to participate, gathering 6,807 responses to the statement Science has put it beyond reasonable doubt that COVID-19 is caused by a virus. The study demonstrates that it is possible to establish a global network to quickly ascertain scientific opinion on a large international scale, with high response rate, low opt-out rate, and in a way that allows for significant (perhaps indefinite) repeatability. Measuring scientific opinion in this new way would be a valuable complement to currently available approaches, potentially informing policy decisions and public understanding across diverse fields. (shrink)

We take up the challenge of developing an international network with capacity to survey the world’s scientists on an ongoing basis, providing rich datasets regarding the opinions of scientists and scientific sub-communities, both at a time and also over time. The novel methodology employed sees local coordinators, at each institution in the network, sending survey invitation emails internally to scientists at their home institution. The emails link to a ‘10 second survey’, where the participant is presented with a single statement (...) to consider, and a standard five-point Likert scale. In June 2023, a group of 30 philosophers and social scientists invited 20,085 scientists across 30 institutions in 12 countries to participate, gathering 6,807 responses to the statement Science has put it beyond reasonable doubt that COVID-19 is caused by a virus. The study demonstrates that it is possible to establish a global network to quickly ascertain scientific opinion on a large international scale, with high response rate, low opt-out rate, and in a way that allows for significant (perhaps indefinite) repeatability. Measuring scientific opinion in this new way would be a valuable complement to currently available approaches, potentially informing policy decisions and public understanding across diverse fields. (shrink)

This study aims to investigate the relationship between job burnout and employee performance in the feed industry during the ASF outbreak. Further, the researchers employed a descriptive-correlational research design in order to analyze the acquired data and produce pertinent findings. Thus, the researchers gathered data from one hundred two (102) feed industry employees. The Maslach Burnout Inventory (MBI) and Individual Work Performance Questionnaire (IWPQ) were employed to ascertain the extent of job burnout experienced by the respondents and evaluate employee performance, (...) respectively. Based on the statistical analysis, there is a significant relationship between job burnout and employee performance. Moreover, the study's findings were thoroughly analyzed and discussed. (shrink)

Despite its effectiveness, limited research has examined the provision of telemental health and how practices may vary according to treatment paradigm. We surveyed 276 community mental health providers registered with a commercial telemedicine platform. Most providers reported primarily offering TMH services to adults with anxiety, depression, and trauma-and stressor-related disorders in individual therapy formats. Approximately 82% of TMH providers reported endorsing the use of Cognitive Behavioral Therapy in their remote practice. The most commonly used in-session and between-session exercises included coping (...) and emotion regulation, problem solving, mindfulness, interpersonal skills, relaxation, and modifying and addressing core beliefs. CBT TMH providers had a higher odds of using in-session and homework exercises and assigning them through postal mail, email or fax methods, as compared to non-CBT TMH providers. TMH providers, regardless of treatment paradigm, felt that assigning homework was neither easy nor difficult and they believed their patients were somewhat-to-moderately compliant to their assigned exercises. CBT TMH providers also collected clinical information from their patients more often than non-CBT TMH providers. They reported being less satisfied with their method, which was identified most often as paper-based surveys and forms. Overall, TMH providers employ evidence-based treatments to their patients remotely, with CBT TMH providers most likely to do so. Findings highlight the need for innovative solutions to improve how TMH providers that endorse following the CBT treatment paradigm remotely assign homework and collect clinical data to increase their satisfaction via telemedicine. (shrink)

Although researchers have investigated the impact of social isolation on well-being, the recent quarantines due to COVID-19 resulted in a social isolation environment that was unique to any examined in the past. Because sleep is one of the endogenous drives that impacts short and long-term health and well-being, it is important to consider how social isolation during the COVID-19 government-mandated quarantines affected sleep and sleep habits. A number of researchers have addressed this question during the last 2 years by examining (...) several concepts related to possible changes in sleep during the quarantines. To best understand these recent results, the current mini review provides a background on the pre-pandemic literature on the effects of social isolation and loneliness with a focus on sleep and then summarizes the recent literature on sleep and sleep habits. In general, sleep was negatively impacted for many people during the pandemics but not all. One group that seemed to benefit from the pandemic in terms of sleep patterns, were younger people who could more easily adapt their sleep times to match their internal chronobiology. Given the potential broad impact of sleep on health and well-being, better understanding how social isolation impacts sleep is an important consideration for individuals, work organizations, and governments. (shrink)

In another tumultuous term of the United States Supreme Court in 2022-2023 a series of critical cases implicate instant and forthcoming changes in multiple fronts that collectively shift the national public health law and policy environment.

Participants in clinical research sometimes view participation as therapy or exaggerate potential benefits, especially in phase I or phase II trials. We conducted this study to discover what methods might improve cancer patients’ understanding of early-phase clinical trials. We randomly assigned 130 cancer patients from three U.S. medical centers who were considering enrollment in a phase I or phase II cancer trial to receive either a multimedia intervention or a National Cancer Institute pamphlet explaining the trial and its purpose. Intervention (...) participants were 32 times more likely to believe that the trial’s purpose was to examine safety and 60 % less likely to believe they would experience long-term benefit or cure. There was no difference in enrollment decision. However, while patients’ understanding of the trial’s purpose improved and expectations of long-term benefit diminished, half the respondents still believed they would experience long-term benefit or cure from participation. Therefore, we conclude that multimedia interventions such as this one may help oncologists to explain the risks and benefits of early-phase cancer trials in a way that patients can more easily understand, helping them to make more informed decisions about participation. But further research into other factors that influence patients’ beliefs about the outcome of enrollment is needed, both to modify the interventions and to determine how malleable patient beliefs are. (shrink)

IntroductionCognitive impairment is a highly prevalent non-motor feature of Parkinson’s disease. A better understanding of the underlying pathophysiology may help in identifying therapeutic targets to prevent or treat dementia. This study sought to identify metabolic alterations in the prefrontal cortex, a key region for cognitive functioning that has been implicated in cognitive dysfunction in PD.MethodsProton Magnetic Resonance Spectroscopy was used to investigate metabolic changes in the PFC of a cohort of cognitively normal individuals without PD, as well as PD participants (...) with either normal cognition, mild cognitive impairment, or dementia. Ratios to Creatine resonance were obtained for glutamate, glutamine and glutamate combined, N-acetylaspartate, myoinositol, and total choline, and correlated with cognitive scores across multiple domains administered to the PD participants only.ResultsWhen individuals retain cognitive capabilities, the presence of Parkinson’s disease does not create metabolic disturbances in the PFC. However, when cognitive symptoms are present, PFC Glu/Cre ratios decrease with significant differences between the PD-NC and PPD groups. In addition, Glu/Cre ratios and memory scores were marginally associated, but not after Bonferroni correction.ConclusionThese preliminary findings indicate that fluctuations in prefrontal glutamate may constitute a biomarker for the progression of cognitive impairments in PD. We caution for larger MRS investigations of carefully defined PD groups. (shrink)

Investigations into the neurobiology of moral cognition are often done by examining clinical populations characterized by diminished moral emotions and a proclivity toward immoral behavior. Psychopathy is the most common disorder studied for this purpose. Although cocaine abuse is highly co-morbid with psychopathy and cocaine-dependent individuals exhibit many of the same abnormalities in socio-affective processing as psychopaths, this population has received relatively little attention in moral psychology. To address this issue, the authors used functional magnetic resonance imaging (fMRI) to record (...) hemodynamic activity in 306 incarcerated male adults, stratified into regular cocaine users (n = 87) and a matched sample of non-cocaine users (n = 87), while viewing pictures that did or did not depict immoral actions and determining whether each depicted scenario occurred indoors or outdoors. Consistent with expectations, cocaine users showed abnormal neural activity in several frontostriatial regions during implicit moral picture processing compared to their non-cocaine using peers. This included reduced moral/non-moral picture discrimination in the vACC, vmPFC, lOFC, and left vSTR. Additionally, psychopathy was negatively correlated with activity in an overlapping region of the ACC and right lateralized vSTR. These results suggest that regular cocaine abuse may lead to affective deficits which can impact relatively high-level processes like moral cognition. Moreover, they add to a growing body of research suggesting an important role for the mesocorticolimbic dopamine pathway in socio-affective processing. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Gleam of Light: Moral Perfectionism and Education in Dewey and EmersonMichael J. McGandyNaoko Saito The Gleam of Light: Moral Perfectionism and Education in Dewey and Emerson American Philosophy Series. Foreword by Stanley CavellNew York: Fordham University Press, 2005. xvi + 210 pp.This book presents the reader with a tantalizing and sometimes frustrating mixture of philosophical enterprises. Saito examines the role of imagination in personal growth and (...) education as presented in the philosophies of Ralph Waldo Emerson (who coined the expression "gleam of light" in "Self-Reliance") and John Dewey. She also joins in conversation the 19th century Emerson, the early 20th century Dewey, and the contemporary Stanley Cavell. Finally, Saito offers insights that will aid educators as they balance the sometime contrary aims of achieving educational standards and inspiring personal development.These are all worthy projects. There is no doubt that each project has relations to the other two and that each gains force and clarification from those relations. Yet it is evident that, within the compass of 160 pages, it is not easy to do all three things and do them well. It is then principally as a standard academic monograph addressing education and imagination in the works of Emerson, Dewey, and Cavell that The Gleam of Light should be considered. Libraries and scholars of American philosophy will want this book on their shelves as a resource on these crucial topics and as a new reading of these important figures in philosophy.Saito is at her best when she engages in textual analysis and comparison in order to bridge the gulf that Cavell claims (see Conditions Handsome and Unhandsome) exists between Dewey and Emerson. Scholars of Emerson and Dewey (and perhaps of Cavell) will find The Gleam of Light an interesting study that highlights important connections among Emerson's concept of imagination, Dewey's idea of impulse, and Cavell's theme of Emersonian moral perfectionism. The book is rich in presentations of texts well-known as well as obscure. The upshot of Saito's reading is that the Emersonian concern for the project of moral perfection is found to be quite alive in Dewey's pedagogical outlook and that questions regarding the goals of Deweyan education can be addressed from the standpoint of the cultivation of the native imaginative capacities of individuals. In sum: Education is a matter of identifing, cultivating, and, when necessary, retrieving the gleam of light intrinsic to each person.Readers interested in Saito's creative and fine reading of these three philosophers will have to be wary, however. In the course of drawing their works into relationship she cannot resist the anachronistic impulse to bring all three into conversation as if they were contemporaries fully aware of each one's respective body of writing. This is interesting rhetorically, but questionable in a work that is firmly grounded in the history of philosophy. Moreover, as it is only Saito who is in the position to create this three-way [End Page 303] conversation, her anachronistic gestures occur at times when she should forthrightly join that conversation and make her own claims.Taking a step back from Saito's close reading of the major texts of these three philosophers, readers will also find a larger argument for ameliorating differences between pragmatism and idealism via an aesthetic analysis of human experience and action. This might be Saito's principal contribution. Looking to Dewey's Experience and Nature and Art as Experience, Saito finds that these works lay more emphasis on individual experience and imagination. It is when one considers experience from the first-person standpoint (appropriately infused with aesthetic categories) that the apparent scientistic quality of Dewey's philosophy is constrained and the Emersonian theme of personhood is highlighted. The claim undergirding this approach is that while idealism and pragmatism differ widely when considered from the standpoints of epistemology and metaphysics, it is in aesthetics that there are grounds for conceptual reconciliation. This is a provocative thesis that bears further consideration by Saito and others.The Gleam of Light is less satisfying when one considers the book from the standpoint of pedagogical theory. Saito aims to contribute to the discussion regarding goal-oriented... (shrink)

Cosmo-nationalism interrogates the rise of national philosophies and their impact on cosmopolitanism and nationalism. -/- The idea of national philosophy carries in it a strange contradiction. We talk about 'German philosophy' or 'American philosophy'. But philosophy has always pictured itself to be the project of universality. It presents itself as something that takes place outside or beyond the national – detachable from language, culture and history. -/- So why do we assign nationalities to philosophies? Building on Jacques Derrida's unpublished seminars (...) on philosophical nationalism, Oisín Keohane claims that national philosophies are a variant of some form of cosmo-nationalism: a strain of nationalism that uses, rather than opposes, ideas in cosmopolitanism to advance the aims of one nation. -/- Key Features Opens up new exciting areas of exploration between nationalism and cosmopolitanism through the concept of the cosmo-national Examines Derrida’s unpublished seminars on philosophical nationalism, showing him to be much more interested in the intersection of philosophy and the social sciences than previously thought Explores three cases: German Philosophy through Kant and Fichte, French Philosophy through Tocqueville and American Philosophy through Emerson. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

B a c k g r o u n d. The article examines the interconnection between the philosophy of nature and the political philosophy of the transcendentalists R. W. Emerson and H. D. Thoreau. For these thinkers, political philosophy was intrinsically linked to their understanding of nature, which they considered the foundation for comprehending social and political processes. Both transcendentalists emphasized the importance of unity with nature as a key factor in personal development. They regarded individual growth as the (...) cornerstone for positive societal changes, with particular attention given to individualism. Their support for the actions of J. Brown exemplified the practical realization of the ideas of political idealism and transcendentalism. In their view, the primary aim of government should be to promote individuality and improve the conditions of human existence, which led them to actively oppose the system of slavery. M e t h o d s. A comprehensive methodological approach was employed to analyze the political philosophy of R. W. Emerson and H. D. Thoreau in the context of their philosophy of nature. This included general scientific methods, historical-philosophical methods, and specific techniques, such as the hermeneutic approach. Additionally, the method of historical reconstruction was used to highlight the socio-political context of their ideas. R e s u l t s. The study revealed the deep integration of Emerson's and Thoreau's political philosophy into their concept of nature, as well as its connection to the socio-political conditions of their era. American transcendentalism occupies a unique place not only in the history of early American philosophy but also within the broader scope of English-speaking philosophy. It blended German idealism, Neoplatonism, and Eastern mysticism, forming a distinctive eclectic doctrine that offered a unique perspective on nature, human nature, rights and freedoms, education, physical labor, individualism, and collectivism. American transcendentalism directly and indirectly influenced the development of American pragmatism, as evidenced in the works of pragmatists such as J. Dewey, C. S. Peirce, and W. James. Its influence is also evident in the literary heritage of H. Melville, N. Hawthorne, W. Irving, and others. C o n c l u s i o n s. The political philosophy of R. W. Emerson and H. D. Thoreau was grounded in their understanding of natural laws, the importance of civic education and education in general, unity with nature, and respect for the individual. They regarded slavery as an unnatural social order, opposition to which they considered a moral duty for citizens aspiring to build a harmonious society. (shrink)

B a c k g r o u n d. The article reveals the connection between the concept of nature of the transcendentalists R.W. Emerson and H.D. Thoreau and the Socio-Political Discourse of the 19th century United States of America. Specific socio-political aspects that formed the basis for the formation of manifestations about nature in the United States in the 19th century were: growing industrialization, the anti-slavery movement, and policies regarding the indigenous population. The article will note the impact (...) of these factors on the formation of the concept of nature. M e t h o d s. The method of historical reconstruction was used to reveal the socio-political context of the philosophy of nature of American transcendentalism. The hermeneutic method was used to interpret the philosophy of nature of R. V. Emerson and G. D. Thoreau, taking into account the socio-political context. A comparative method was used to find common and distinctive features in the philosophical views of American thinkers. The problem-based method made it possible to focus attention precisely on the problems in philosophical views and on the ways of their solution. And the contextual method, the purpose of which is to clarify the context of the appearance and development of a particular idea, this article focuses on the concept of "nature". R e s u l t s. As a result of the study, affinities between the theorization of abolitionism, reflection on industrialization, debate on the indigenous population and the philosophy of nature of American transcendentalism were revealed. C o n c l u s i o n s. The philosophy of the nature of American transcendentalism of R. W. Emerson and H. D. Thoreau is deeply rooted in the socio-political context of the United States of America before the Civil War and became the theoretical foundation of the abolitionist movement. The concept of nature in the philosophy of American transcendentalism is closely related to the socio-political discourse of the United States of America in the 19th century. Radical changes in society before the civil war stimulated the development of both social philosophy and the philosophy of nature. (shrink)

Ten of the twelve essays in this fine collection treat subjects that are relevant to any reasonably comprehensive understanding of the nature of the history of science. The first four essays are either completely or largely historiographical. Each explores the extent to which the natural sciences have been, or should be, seen as central to the Scottish Enlightenment. As all four provide extended descriptive historiographies, there is extensive repetition here, but as the four also offer radically different answers, they are (...) worth reading.In the first essay Paul Wood argues that Dugald Stewart created an imaginary picture of the Scottish Enlightenment that has influenced almost all subsequent interpretations of the movement. These interpretations have promoted the idea that there was a coherent “Scottish school” of philosophy of which David Hume and Francis Hutcheson were the cofounders; that the Scottish school emphasized moral philosophy and social theory; and that it included figures from Glasgow, Edinburgh, and Aberdeen. Wood claims that Stewart downplayed the relationship between natural knowledge and social theory, except for some minor methodological commonalities, for several reasons. In part, he desperately wanted to maintain the mind‐body dualism that characterized the Scottish school. In addition, his main statement on the Scottish Enlightenment appeared as an essay on the history of the progress of metaphysics and morals that was paired with John Leslie's essay on the progress of the natural sciences in the supplement to the fourth edition of the Encyclopaedia Britannica, and he was simply responding to the limits of his assignment. Regardless of his motives, one major consequence of Stewart's approach has been the exclusion of the natural sciences from a central role in most subsequent interpretations of the Scottish Enlightenment not written by historians of science—an exclusion Wood laments.The second essay, by John Robertson, seems, on one level, almost designed to prove Wood's main point, for it explicitly denies natural science a significant role. For Robertson, moral philosophy, history, and, above all, political economy are at the core of Scottish concerns. He departs from Stewart, however, by insisting on a fundamental opposition between Hume and Hutcheson and by arguing that the Scottish Enlightenment would be better understood as part of a broader European Enlightenment, with less patriotic fervor about Scots exceptionalism.Richard Sher's essay on what book history can tell us about science and medicine in the Scottish Enlightenment is remarkably insightful and illuminating; it left me waiting with great anticipation for his book‐length study on the subject. Although Sher rejects Roger Emerson's claims that the natural sciences were the driving force for the Enlightenment in Scotland, he insists that science and medicine were important. He then goes on to suggest a series of fascinating ways in which characteristics of the book trade both shaped and can illuminate the place of science.Among the other essays likely to interest historians of science are those by Anita Guerrini, John Wright, and Fiona MacDonald. These authors explore aspects of medical theory and medical care in very different but very illuminating ways. One other related set of essays consists of pieces by James Moore, Christopher Berry, and Alexander Broadie, all of which focus on aspects of the theorized relationship between science and religion. Here, the major theme is the difference in emphases between those who followed the ancient materialists in seeing fear as the primary motive in the origins of religion and those who emphasized some version of the design argument.This volume provides a good introduction to the current state of interpretations of the Scottish Enlightenment, and its special emphasis on the place of science among eighteenth‐century Scottish intellectuals should make it attractive to many readers of Isis. (shrink)

In this engaging book, Douglas Anderson begins with the assumption that philosophy—the Greek love of wisdom—is alive and well in American culture. At the same time, professional philosophy remains relatively invisible. Anderson traverses American life to find places in the wider culture where professional philosophy in the distinctively American tradition can strike up a conversation. How might American philosophers talk to us about our religious experience, or political engagement, or literature—or even, popular music? Anderson’s second aim is to find places (...) where philosophy happens in nonprofessional guises—cultural places such as country music, rock’n roll, and Beat literature. He not only enlarges the tradition of American philosophers such as John Dewey and William James by examining lesser-known figures such as Henry Bugbee and Thomas Davidson, but finds the theme and ideas of American philosophy in some unexpected places, such as the music of Hank Williams, Tammy Wynette, and Bruce Springsteen, and the writingsof Jack Kerouac.The idea of “philosophy Americana” trades on the emergent genre of “music Americana,” rooted in traditional themes and styles yet engaging our present experiences. The music is “popular” but not thoroughly driven by economic considerations, and Anderson seeks out an analogous role for philosophical practice, where philosophy and popular culture are co-adventurers in the life of ideas. Philosophy Americana takes seriously Emerson’s quest for the extraordinary in the ordinary and James’s belief that popular philosophy can still be philosophy. (shrink)